Monthly Archives: May 2017

In the very recent article below (from TheScientist.com), the two authors suggest that there should be a common, online centralized streamlined submission process that would serve all journals. From such an internet web site, an author could submit (and re-submit) … Continue reading →

HGNC Newsletter Spring 2017 There are currently 40,979 approved symbols New collaboration with TGMI The HGNC is excited to announce that we are now members of the Wellcome Trust-funded Transforming Genetic Medicine Initiative (TGMI). This project strives to facilitate the … Continue reading →

This (very brief note in Nature) summarizes the latest in the sad state-of-affairs in science, and scientific publications, in these new predatory journals. Can we ever again return to honest science and integrity –– without so much fraud and corruption..?? … Continue reading →

Every trait (phenotype) reflects the contribution of one or a few or many hundred or thousands of genes (DNA sequence; our genome), plus epigenetic effects (our ~200 epigenomes that can differ in each of our ~200 different cell types), and … Continue reading →

A major goal in all of biology and medicine is to understand the function of every gene in the human genome. Loss-of-function (LOF) mutations can disrupt both copies of a given gene in humans. Thus, phenotypic analysis of such ‘human … Continue reading →

Aboriginal Australians represent one of the longest continuous cultural complex populations known. Archaeological evidence indicates that Australia and New Guinea were initially settled ~50,000 years ago. However, little is known about the processes underlying the enormous linguistic and phenotypic diversity … Continue reading →

The Golden Rule used to be that “all information needed for any phenotype (trait) is right there in our DNA.” Then the concept of epigenetic effects started raising its ugly head. “Epigenetics” represents genetic regulation outside of what can be … Continue reading →

In the 1960s, things were simple. Genes were made from DNA, which was transcribed into RNA, which was then translated in the cytoplasm (in ribosomes) into proteins (i.e. the gene products). Then people realized that transcribed RNA includes both exons … Continue reading →