Category Archives: Center for Environmental Genetics

Functional interpretation, cataloging, and analysis of 1,341 glucose-6-phosphate dehydrogenase variants

During the 1980s, there was a time when we wondered if any drug-metabolizing-enzyme (DME) gene might have more than one or two mutant variants. Then, in the late 1980s came the first paper in which five variant alleles were cloned … Continue reading

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ZOONOMIA 240 Mammalian Genomes sequenced and compared (!!!)

The attached pdf file is a follow-up of our GEITP blog sent out on 29 Apr 2023, which was a summary in Nature of the collection of papers published in the 28 Apr 2023 issue of Science. The first two … Continue reading

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Lifespan: Why We Age—and Why We Don’t Have To

I’m 27% of the way through this long book. The grammar is exceptionally remarkable for transitioning complex molecular biology into layman’s language — so that non-scientists (and EVEN PHYSICIAN) can understand. Author Sinclair is an Australian who has a lab … Continue reading

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Study of Hospitalizations in Canada Quantifies Benefit of COVID-19 Vaccine to Reduce Death, ICU Admissions

Pasted below is a reasonable study (summarized in Medscape) that shows us how tremendously dramatic the effects of the COVID-19 vaccine were in terms of saving lives during the pandemic. One caveat not mentioned, however, is the (relatively small, but … Continue reading

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Neurons that connect without synapses

Evolutionarily, which animal came first? Sponges or comb jellies? Concerning the evolution of animal nervous systems, it had been quite well accepted that all neurons connect to each other with synapses, and that the nervous system arose only once in … Continue reading

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A.I. language models open a potential Pandora’s box of medical research fraud

This recent online article (about ChatGPT; summarized from an article published in the open-access journal Patterns) — furthers the cause for concern about this AI-based program. Specifically, if Drug A is maliciously <> or <> to be better than Drug … Continue reading

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18 Spectacularly Wrong Predictions Made around the the First Earth Day, 1970

By the way, HAPPY EARTH DAY. This article is from 2 years ago — but nothing has changed. Nonscientific hysteria is running as high as ever. ☹☹☹ DwN 18 Spectacularly Wrong Predictions Made around the Time of the First Earth … Continue reading

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Is glyphosate toxic or carcinogenic? This Latest Review, full of sound and fury, seems to signify nothing

GEITP has had previous discussions about the herbicide, glyphosate. The attached review is the latest summary of where this controversial chemical stands. Glyphosate is the most applied agricultural chemical worldwide and has become nearly ubiquitous throughout the environment. Glyphosate is … Continue reading

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Call for Papers & Thematic Issues—Current Microwave Chemistry

With more than 25,000 “open-access, rapid-publication with fake revewers, predatory journals” that have been created, and continue to explode, since about 2012 — you can imagine the difficulty in trying to come up with a new name (and initials that … Continue reading

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Machine learning and artificial intelligence in physiologically based pharmacokinetic (PBPK) modeling

Artificial Intelligence (AI) and Machine Learning (ML) are two rapidly advancing fields of research, which will clearly play important roles in gene-environment interactions (GxE), as well as almost every venue of scientific study. Hence, GEITP is introducing this topic here. … Continue reading

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