Monthly Archives: June 2019

As these GEITP pages have continued to emphasize: Multifactorial phenotypes — including complex diseases (e.g. type-2 diabetes, major depressive disorder), quantitative traits (e.g. body mass index, height), drug efficacy and adverse drug reactions, and responses to environmental toxicants (e.g. dioxin, … Continue reading →

As these GEITP pages have continued to emphasize: Multifactorial phenotypes — including complex diseases (e.g. type-2 diabetes, cancer, major depressive disorder), quantitative traits (e.g. height, body mass index), drug efficacy and adverse drug reactions, and responses to environmental toxicants (e.g. … Continue reading →

Dopamine is a neurotransmitter molecule that influences brain pathways — involved in motivation, movement, reasoning/perception, and reward-driven learning. How dopamine contributes to such seemingly-unrelated varied behaviors is the topic of this GEITP email. In fact, understanding the biochemical and genetic … Continue reading →

Let’s Teach Factual Climate Science In Schools Published June 22, 2019 | By Daniel W. Nebert Daniel W. Nebert Twenty-one Oregon teenagers have spent four years urging our federal government to take action on “climate change.” They found themselves back … Continue reading →

One of the GEITP topics is to understand individual response to drugs and other environmental signals including toxicants. This “response” comprises the genetic architecture of each person or lab animal. To break it down further, this “response” includes genetics, epigenetics … Continue reading →

This information does not bode well for predictions of further “global warming” — In fact, the lowered solar activity could cause “global cooling” again. Ugh. Colder, snowier winters..?? ☹ Sun spotless for 33 days straight – airline travelers getting dosed … Continue reading →

Transgenic Metarhizium rapidly kills mosquitoes in a malaria-endemic region Nebert, Daniel (nebertdw) Thu 6/20, 2:07 PM The topic of today’s GEITP article is using a genetically-modified organism (GMO) to control a pest; this is an interesting “gene-environment interactions” type of … Continue reading →

This article is a summary (Research Brief 294) of a recent project funded by the NIEHS Superfund Research Program (SRP). I contacted Dr. Monte, and our email correspondence is located below. DwN New Method Proposed to Screen Chemicals Quickly for … Continue reading →

These GEITP pages have often discussed the fact that complex diseases almost always represent multifactorial phenotypes (traits) — (e.g. hypertension, schizophrenia, mental depressive disorder, cancer, autoimmunity, obesity, and diabetes) — which reflect contributions from genetics (alterations in DNA sequence), epigenetic … Continue reading →