Monthly Archives: July 2019

Studies on the occurrence of cytochrome P450 genes (CYPs) in viruses

Posted on July 31, 2019 by DWN

Cytochromes P450 (CYPs) are important enzymes that undoubtedly appeared very early in evolution — because these genes are found today in archaebacteria, eubacteria, plants, fungi and animals — as well as in several dozen viruses. In mammals, these enzymes carry … Continue reading →

Posted in Center for Environmental Genetics | Comments Off on Studies on the occurrence of cytochrome P450 genes (CYPs) in viruses

How do genes come about — in the first place ???

Posted on July 27, 2019 by DWN

These GEITP pages have the over-reaching theme of gene-environment interactions. This includes evolution of life (archaebacteria, eubacteria, plants, fungi & animals) and, accordingly, evolution of genes (especially in response to environmental stress, i.e. climate, diet, need for food & reproduction … Continue reading →

Posted in Center for Environmental Genetics | Comments Off on How do genes come about — in the first place ???

High-throughput single-cell ChIP-seq identifies heterogeneity of chromatin states in breast cancer

Posted on July 24, 2019 by DWN

As these GEITP pages have often discussed, in order to understand the contribution of genes and other factors to any selected phenotype (trait, such as schizophrenia, obesity, response to a drug, or response to an environmental toxicant) — assays have … Continue reading →

Posted in Center for Environmental Genetics | Comments Off on High-throughput single-cell ChIP-seq identifies heterogeneity of chromatin states in breast cancer

Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk

Posted on July 23, 2019 by DWN

These GEITP pages maintain the theme of gene-environment (GxE) interactions. Autism spectrum disorder (ASD) has often been included as one of our topics, because this fascinating complex disease is a multifactorial trait — that might include not only GxE interactions, … Continue reading →

Posted in Center for Environmental Genetics, Gene environment interactions | Comments Off on Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk

Genetic analyses of diverse populations improves discovery for complex traits

Posted on July 22, 2019 by DWN

This article [attached] was described earlier — in these GEITP pages (on July 3rd) in layman’s terms [pasted again at the bottom of this email]. The Population Architecture using Genomics and Epidemiology (PAGE) study was developed by the National Human … Continue reading →

Posted in Center for Environmental Genetics | Comments Off on Genetic analyses of diverse populations improves discovery for complex traits

The population history of northeastern Siberia since the Pleistocene

Posted on July 22, 2019 by DWN

Far northeastern Siberia was the gateway to the Americas for ancient humans; today it is home to diverse cultures whose members speak many languages. During the Late Pleistocene period [i.e. the Last Glacial Period (LGP), lasting from ~126,000 to ~11,700 … Continue reading →

Posted in Evolution and genetics | Comments Off on The population history of northeastern Siberia since the Pleistocene

Targeting metabolism to regulate immune responses in autoimmunity and cancer

Posted on July 21, 2019 by DWN

These GEITP pages include topics where a “signal” (from the environment; or from another cell or organ) is received by a cell, which then responds (using its genes, genome, epigenome) to that signal. Hence, this review article [see attached], which … Continue reading →

Posted in Center for Environmental Genetics | Comments Off on Targeting metabolism to regulate immune responses in autoimmunity and cancer

Excellent summary from several difference scientific sources on global climate change

Posted on July 20, 2019 by DWN

This is an EXCELLENT summary from several difference scientific sources — appearing in https//finance.townhall.com — that should (or could) clarify the minds of non-scientists who do not understand Climatology, and how complex it is. Anyone with an open mind, or … Continue reading →

Posted in Center for Environmental Genetics | Comments Off on Excellent summary from several difference scientific sources on global climate change

excellent summary from several difference scientific sources

Posted on July 20, 2019 by DWN

This is an EXCELLENT summary from several difference scientific sources — appearing in https//finance.townhall.com — that should (or could) clarify the minds of non-scientists who do not understand Climatology, and how complex it is. Anyone with an open mind, or … Continue reading →

Posted in Center for Environmental Genetics | Comments Off on excellent summary from several difference scientific sources

Human CRISPR twins are predicted to have “shortened life spans”

Posted on July 19, 2019 by DWN

hese GEITP pages have followed the story, the ethical dilemma, of biophysicist Jiankui He (in late 2018, from the Southern Univ of Sci & Technol in Shenzhen, China), who reported births of twin girls whose genomes had been edited using … Continue reading →

Posted in Evolution and genetics | Comments Off on Human CRISPR twins are predicted to have “shortened life spans”