-
Recent Posts
- Meta-analysis of GWAS of gestational duration, and spontaneous preterm birth, identifies new maternal risk loci
- The crusade against carbon dioxide and integrity in climate science
- Pioneers of mRNA COVID vaccines win the 2023 Medicine Nobel
- Tasmanian tiger RNA is first to be recovered from an extinct animal
- How to train your jellyfish: brainless box jellies learn from experience
Recent Comments
Archives
- October 2023
- September 2023
- August 2023
- July 2023
- June 2023
- May 2023
- April 2023
- March 2023
- February 2023
- December 2022
- November 2022
- October 2022
- September 2022
- August 2022
- July 2022
- June 2022
- May 2022
- April 2022
- March 2022
- February 2022
- November 2021
- October 2021
- September 2021
- August 2021
- July 2021
- June 2021
- May 2021
- March 2021
- February 2021
- January 2021
- December 2020
- November 2020
- October 2020
- September 2020
- August 2020
- July 2020
- June 2020
- May 2020
- April 2020
- March 2020
- February 2020
- January 2020
- December 2019
- November 2019
- October 2019
- September 2019
- August 2019
- July 2019
- June 2019
- May 2019
- April 2019
- March 2019
- February 2019
- January 2019
- December 2018
- November 2018
- October 2018
- September 2018
- August 2018
- July 2018
- June 2018
- May 2018
- April 2018
- March 2018
- February 2018
- January 2018
- December 2017
- November 2017
- October 2017
- September 2017
- August 2017
- July 2017
- June 2017
- May 2017
- April 2017
- March 2017
- February 2017
- January 2017
- December 2016
- November 2016
- October 2016
- September 2016
- August 2016
- July 2016
- June 2016
- May 2016
- April 2016
- March 2016
- February 2016
- January 2016
- September 2006
- September 1995
- August 1995
- January 1995
- September 1994
- March 1994
- January 1994
Categories
Meta
-
Recent Posts
- Meta-analysis of GWAS of gestational duration, and spontaneous preterm birth, identifies new maternal risk loci
- The crusade against carbon dioxide and integrity in climate science
- Pioneers of mRNA COVID vaccines win the 2023 Medicine Nobel
- Tasmanian tiger RNA is first to be recovered from an extinct animal
- How to train your jellyfish: brainless box jellies learn from experience
Recent Comments
Archives
- October 2023
- September 2023
- August 2023
- July 2023
- June 2023
- May 2023
- April 2023
- March 2023
- February 2023
- December 2022
- November 2022
- October 2022
- September 2022
- August 2022
- July 2022
- June 2022
- May 2022
- April 2022
- March 2022
- February 2022
- November 2021
- October 2021
- September 2021
- August 2021
- July 2021
- June 2021
- May 2021
- March 2021
- February 2021
- January 2021
- December 2020
- November 2020
- October 2020
- September 2020
- August 2020
- July 2020
- June 2020
- May 2020
- April 2020
- March 2020
- February 2020
- January 2020
- December 2019
- November 2019
- October 2019
- September 2019
- August 2019
- July 2019
- June 2019
- May 2019
- April 2019
- March 2019
- February 2019
- January 2019
- December 2018
- November 2018
- October 2018
- September 2018
- August 2018
- July 2018
- June 2018
- May 2018
- April 2018
- March 2018
- February 2018
- January 2018
- December 2017
- November 2017
- October 2017
- September 2017
- August 2017
- July 2017
- June 2017
- May 2017
- April 2017
- March 2017
- February 2017
- January 2017
- December 2016
- November 2016
- October 2016
- September 2016
- August 2016
- July 2016
- June 2016
- May 2016
- April 2016
- March 2016
- February 2016
- January 2016
- September 2006
- September 1995
- August 1995
- January 1995
- September 1994
- March 1994
- January 1994
Categories
Meta
Monthly Archives: January 2019
Assembly of complete genome from 910 Africans: ~10% more DNA than the current human reference genome !!!
From the time of the first publication of the “complete human genome sequence” [Feb 2001; which was hardly “complete”, and which champagne celebration party at the National Library of Medicine in Bethesda, I (fortunately or unfortunately) attended?], the human genome … Continue reading
Posted in Center for Environmental Genetics
Comments Off on Assembly of complete genome from 910 Africans: ~10% more DNA than the current human reference genome !!!
Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
As with the previous GEITP email, the topic of this study [see attached report; note there are a bazillion coauthors on this publication J] is again about polygenic risk score (PRS) — which is the latest advance/improvement on genome-wide association … Continue reading
Posted in Center for Environmental Genetics
Comments Off on Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
Leveraging Polygenic Functional Enrichment to Improve GWAS Power
Genome-wide association studies (GWAS) represent the prevailing approach for identifying risk loci for common diseases and complex traits — such as schizophrenia, obesity, type-2 diabetes, drug efficacy or response to environmental toxicants. In the study design of GWAS, millions of … Continue reading
Posted in Center for Environmental Genetics
Comments Off on Leveraging Polygenic Functional Enrichment to Improve GWAS Power
Low-dose A-bomb radiation lengthen lifespan and decreases cancer mortality — compared with un-irradiated individuals
COMMENT: Agreed, Jim. It is important for toxicologists and epidemiologists to realize that (very often, if not always): a small amount of a chemical — or in the case of this article, atom bomb radiation — can be beneficial; a … Continue reading
Posted in Center for Environmental Genetics
Comments Off on Low-dose A-bomb radiation lengthen lifespan and decreases cancer mortality — compared with un-irradiated individuals
Transcriptomics analysis to study dysregulation in autism spectrum disorder, schizophrenia, and bipolar disorder
Many large whole-genome sequenncing (WGS) consortia are searching for genetic pathways in clinical disorders such as autism spectrum disorder (ASD), schizophrenia (SCZ), and bipolar disorder (BD) — hoping to develop novel drugs to treat these three common psychiatric disorders that … Continue reading
Posted in Center for Environmental Genetics
Comments Off on Transcriptomics analysis to study dysregulation in autism spectrum disorder, schizophrenia, and bipolar disorder
Sphynolactone-7 is a potent stimulant — that induces parasitic plant germination, causing it to die
This topic might seem a little bit bizarre, or obtuse — as far as the gene-environment interactions theme of these GEITP pages. On the other hand, it might reflect my subconscious desire to have been a plant molecular biologist. However, … Continue reading
Posted in Center for Environmental Genetics
Comments Off on Sphynolactone-7 is a potent stimulant — that induces parasitic plant germination, causing it to die
Receptor for IRISIN — the exercise-induced hormone, has now been identified
One might consider the topic for today’s gene-environment interactions a bit unusual: “exercise” in this case is “the environment”, and the response to this environmental signal is “the genes” in the signaling pathways that aid in bone formation and burning … Continue reading
Posted in Center for Environmental Genetics
Comments Off on Receptor for IRISIN — the exercise-induced hormone, has now been identified
In Remembrance of: Luigi Luca Cavalli-Sforza (1922–2018)
This is just a brief GEITP note to report the passing of Luigi Luca Cavalli-Sforza, who died at home in Belluno, Italy, 31 Aug 2018; next week would have been his 97th birthday. Professor Cavalli-Sforza was past president of the … Continue reading
Posted in Center for Environmental Genetics
Comments Off on In Remembrance of: Luigi Luca Cavalli-Sforza (1922–2018)
Millions of People Wrongly Believe They Have Food Allergies
This article just appeared in Time magazine. What genetic composition (genes) is it that people have — when they respond to foods (environment) — resulting in a “true food allergy” for some, versus a “psychogenic food allergy” for just about … Continue reading
Posted in Center for Environmental Genetics
Comments Off on Millions of People Wrongly Believe They Have Food Allergies
Machine-learning: The Hunt for the Cause of Acute Flaccid Myelitis (AFM)
A “mysterious” disease has been affecting many dozens of people (at least in the U.S.), and scientists are trying to understand what the “signal” (the environment) is, and what genetic architecture (underlying genetic basis of a trait, and its variational … Continue reading
Posted in Center for Environmental Genetics
Comments Off on Machine-learning: The Hunt for the Cause of Acute Flaccid Myelitis (AFM)