Monthly Archives: June 2018

Dear Dr. Nebert, this is a very interesting paper – thank you. I agree with the authors, for most part. In addition to the weakness that they reported, I think DIP-seq has its inherent drawbacks. Without bisulfite modification, the methylation … Continue reading →

These two very recent publications [see attached] are the latest in a long series –– on the topic of the Linear No-Threshold (LNT) Model, which (since about 2o11) has been carefully dissected historically by Ed Calabrese (School of Public Health, … Continue reading →

We also learned a similar lesson regarding artifacts through the history of proteomics technologies –– particularly from protein-interactions studies that rely on immunoprecipitation as the first step. This ultimately led to a database of “usual suspects” that was later more … Continue reading →

This BREAKTHROUGH paper (reported today in FRONTLINE GENOMICS) is very important to those in the field (e.g. Sean Zhang), so I have moved it “to the front of the QUEUE.” There is nothing worse than spending a lot of time, … Continue reading →

As these GEITP pages keep harping on –– the factors that contribute to any trait (response to a drug or environmental toxicant, hair color, height, blood pressure, risk of type-2 diabetes, risk of autism spectrum disorder, etc.) include: genotype (DNA … Continue reading →

This is just what my late son had been interested in, and predicting, since about 2000. (It was part of his job.) Solar activity (sunspot frequency) has become incredibly quiet during Cycles 23 and especially Cycle 24. The last time … Continue reading →

This is a recent editorial in Nature. DwN New human gene (increased) tally reignites debate Some fifteen years after the human genome was sequenced, researchers still can’t agree on how many genes it contains ––––Cassandra Willyard One of the earliest … Continue reading →

his topic is a bit on the periphery of ‘Gene-Environment Interactions,’ but –– without Life on Earth –– we wouldn’t have genes to interact with the environment. 🙂 How and Why did Life come to exist on this planet? Is … Continue reading →

The breakthrough/landmark study was published recently in J Am Med Assn Psychiatry, but this article on MedScape today is what caught my attention. Every one of us has had experience with family members, relatives, neighbors, and/or friends who have seen … Continue reading →

It is well known that the sex (i.e. whether it’s male or female gender) of certain reptiles can be determined by ambient temperatures of the environment, although the precise molecular mechanism has remained elusive. What is it –– that allows … Continue reading →