Monthly Archives: April 2016

LNTgate: How scientific misconduct by the U.S. NAS led to governments adopting LNT for cancer risk assessment, although many discrepancies existed

Posted on April 29, 2016 by DWN

Below is the latest report in the continuing saga about uncovering the role of the U.S. National Academy of Sciences (NAS) Biological Effects of Atomic Radiation (BEAR) I Committee Genetics Panel in the adoption of the linear-dose theshold (LNT) response … Continue reading →

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Tumor progression is similar in many many ways to evolution (in an abbreviated time scale)

Posted on April 28, 2016 by DWN

Although mutations in cell populations and allelic frequencies in organismal populations are obviously not equivalent, the idea to halt therapy when some sensitive cells remain is really a fairly old idea:  40 years ago, with integrated pest management (IPM) came … Continue reading →

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“Polypharmacy” is the clinical term for drug-drug interactions (DDIs) in clinical pharmacy

Posted on April 27, 2016 by DWN

This article appeared in a recent issue of the New York Times. Each drug can be considered as “an environmental chemical”, with regard to studying one drug’s effect on a patient, or the patient’s response to that one drug.  REPOSTED … Continue reading →

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GLUTEN: DEFINITION, STRUCTURE, PROPERTIES

Posted on April 27, 2016 by DWN

8 FEBRUARY 2015 DR. NICOLA TAZZINI What is gluten? Gluten Fig. 1 – Wheat Gluten is not a single protein but a mixtureof cereal proteins, about 80% of its dry weight (for example gliadins and glutenins in wheat grains), lipids, … Continue reading →

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Traces of arsenic

Posted on April 26, 2016 by DWN

I am guessing that some of those on my emailing lists might want to argue your comment about “there is NO safe level of arsenic“. DOSE is certainly important and “Alles ist Gift” (everything is poison at some dose). So, … Continue reading →

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Having “disease mutational variants” (genotype) but not exhibiting the disease (phenotype)

Posted on April 25, 2016 by DWN

This is a very interesting exciting study, a great example of “thinking outside the box”. Genetic studies of human Mendelian diseases (one or few mutations in one or few genes) have traditionally focused on detection of the disease-causing mutations in … Continue reading →

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Tumor progression is similar in many many ways to evolution (in an abbreviated time scale)

Posted on April 24, 2016 by DWN

This editorial article [below] comes as no surprise. Many of us were thinking, and saying, and talking about, this phenomenon, … way back in the 1970s. And it is exactly what makes cancer chemotherapy so extremely challenging. Researchers have long … Continue reading →

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CAUTION: Corruption in “scientific publications” is increasing at a logarithmic rate !!

Posted on April 22, 2016 by DWN

Several colleagues have shared with me their pain, annoyance, and inconvenience of receiving 10, 20 or 40 such emails EVERY DAY, seven days a week. Since 2010, the number of “open-access online scientific journals” has increased from 3,000 to 16,000 … Continue reading →

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“Experimental scientific proof of “evolution in action”

Posted on April 22, 2016 by DWN

This is a recent article from Genetic Engineering News Genetic Study of Darwin’s Finches Catches Evolution in Action The medium ground finch (Geospiza fortis) diverged in beak size from the large ground finch (Geospiza magnirostris) on Daphne Major Island, Galápagos, … Continue reading →

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What Is the Tree of Life? And what does that mean?

Posted on April 15, 2016 by DWN

A universal Tree of Life (TOL) has long been a goal of molecular phylogeneticists. However, reticulation (i.e. a pattern resembling a net, instead of a “tree” with a single root) at the level of genes––and possibly at the levels of … Continue reading →

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