Monthly Archives: May 2022

FGF17 in “young CSF” is a tonic for memory ??

Age-related cognitive decline should be a concern to all of us(!!). Whereas a healthy diet and regular exercise can help slow down or prevent this decline, as yet there are no treatments to reverse gradual diminution in memory. As a … Continue reading

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Human Genome Nomenclature Committee (HGNC) NewsLetter. spring 2022

Update on genes with the ‘stable’ tag We now have 2871 gene symbols tagged as ‘stable’ as of May 11th 2022, which is an increase of 50 genes since our Winter newsletter. Examples of genes within the new stable set … Continue reading

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Human gut bacteria produce ΤΗ17-modulating bile acid metabolites

Bile acids are steroid-like natural products that are secreted into the gastrointestinal (GI) tract of vertebrate animals after eating — where they act as “detergents” that aid in digestion, as well as ligands for host receptors. In the gut, host-derived … Continue reading

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Perspectives on rigor and reproducibility in single-cell genomics (scRNAseq)

Single-cell genomics” is a “hot button topic” these days, and these techniques are beginning to transform biological research. One burning question — ever since this technology first appeared on the horizon is: how reproducible are their findings? This invited “Perspective” … Continue reading

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“Completing” the human genome (this time, for real ??)

From: Nebert, Daniel (nebertdw) Sent: den 9 maj 2022 00:25 Subject: “Completing” the human genome (this time, for real ??) #2 The attached articles accompany the “human genome sequence story” — sent to everyone within the past hour. From left … Continue reading

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Human Single-Cell Transcriptome CellAtlas

Our understanding of how individual cells form distinct tissues and organs, and how each cell interacts with one another — is incomplete. Recent single-cell RNA sequencing (scRNAseq) analyses have described the landscapes of individual cell-types, along with their abundance and … Continue reading

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“Life” on Earth can be weird (!!!)

Two miles underground, strange bacteria are found thriving by Chad Boutin Oct. 20, 2006 A Princeton-led research group has discovered an isolated community of bacteria nearly two miles underground that derives all of its energy from the decay of radioactive … Continue reading

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The SOLVAY Prize recognizes the mRNA pioneer whose findings led to the mRNA COVID vaccines

This brief story, published in Nature — represents the follow-up of Dr. Katalin Karikó, an obscure scientist quietly working alone in the lab, who first designed an mRNA construct that was successful in having intact messenger RNA (mRNA) enter living … Continue reading

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