Monthly Archives: November 2020

Some of you might be interested in the latest news from the Human Genome Nomenclature Committee (HGNC). DwN

Coming soon – an improved search for genenames.org We are excited to announce that we are finalising a new version of the search engine for genenames.org. The look and feel will not significantly change but the search will feature an … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Some of you might be interested in the latest news from the Human Genome Nomenclature Committee (HGNC). DwN

Advances in COVID-19 vaccine development, described for the lay person

I cannot find the source (and author) of this article — but it is an excellent lay summary of why these vaccines are being developed so rapidly and successfully, despite no vaccines to coronaviruses ever having been successful, prior to … Continue reading

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In contrast to two excellently designed and executed Phase-3 clinical trials by BNT-Pfizer and Moderna reported several weeks ago — detailed below are the trials and tribulations of several clinical COVID-19 trials by AstraZeneca, run in different countries, and descibed attempts at cherry-picking and piecemeal analysis in order to make the data look good. This is a good example of what can happen in science (and perhaps actually happens too often). ☹

HILDA BASTIAN 11.25.2020 08:00 AM The AstraZeneca Covid Vaccine Data Isn’t Up to Snuff There’s been even additional good news this week, this time from the Oxford-AstraZeneca trials. But a closer look reveals some very shaky science. THE MAKERS OF … Continue reading

Posted in Center for Environmental Genetics | Comments Off on In contrast to two excellently designed and executed Phase-3 clinical trials by BNT-Pfizer and Moderna reported several weeks ago — detailed below are the trials and tribulations of several clinical COVID-19 trials by AstraZeneca, run in different countries, and descibed attempts at cherry-picking and piecemeal analysis in order to make the data look good. This is a good example of what can happen in science (and perhaps actually happens too often). ☹

Repurposed Antidepressant Shows Early Promise in COVID-19

Repurposed Antidepressant Shows Early Promise in COVID-19 Megan Brooks November 19, 2020 Read Comments Early treatment with the antidepressant fluvoxamine (Luvox) may help prevent respiratory deterioration in patients with mild symptomatic COVID-19, results of a preliminary randomized controlled trial suggest. … Continue reading

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A Commericial Sunscreen Modulates Aryl Hydrocarbon Receptor-Signaling in Keratinocytes and Inhibits CYP1A1 and CYP1B1 Enzyme Activities

This topic involves gene-environment interactions. Octinoxate (a sunscreen) is the “environmental signal”, and genetic activation via aryl hydrocarbon receptor (AHR)-signaling represents the “response to the signal.” We are constantly exposed to varying levels of ultraviolet radiation (UVR) from the sun … Continue reading

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