Category Archives: Center for Environmental Genetics

SCIENTIFIC AUTOBIOGRAPHY

I received an invitation in July 2022 — to write “my scientific autobiography,” to be published in the 2024 issue of Annual Review of Pharmacology and Toxicology (APRT). The rules involved a “20-page maximum, which should include proposed figures and … Continue reading

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A Mammalian DNA Methylation Landscape

As this GEITP group has discussed numerous times, each person’s overall genetic architecture (landscape) represents the combination of differences in our: [a] genetics (e.g., DNA sequence changes); [b] epigenetics (chromosomal but not involving DNA sequence); [c] environmental effects (cigarette smoking, … Continue reading

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Power of inclusion: Enhancing polygenic prediction with admixed individuals (simplified)

I apologize. Yesterday’s GEITP blog was regarded by some “as a bit difficult to understand” (i.e., “more basic background” is needed, please). So, here goes: For more than two decades, genome-wide association studies (GWASs) have unequivocally shown that common complex … Continue reading

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Power of inclusion: Enhancing polygenic prediction with admixed individuals

Polygenic scores (PGSs) are used for combining genetic effects into the individual-level genetic liability of diseases or non-disease traits (e.g., risk of type-2 diabetes or schizophrenia; risk of lung cancer as a function of cigarettes smoked, or skin cancer as … Continue reading

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**HGNC Newsletter** Autumn 2023

The Human Genome Organization (HUGO) was conceived in 1988 at the first meeting on genome mapping and sequencing at Cold Spring Harbor. Its original purpose was to promote international collaborative efforts to study the human genome and to address the … Continue reading

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CO2 Rocks! From Hot Rocks to Cool Rocks

CO2 Rocks! From Hot Rocks to Cool Rocks By Bob Hoye When reviewing the history of our atmosphere, it is fascinating that at first it was all atmosphere and no Earth. And it was mainly hydrogen. Then, due to the … Continue reading

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Meta-analysis of GWAS of gestational duration, and spontaneous preterm birth, identifies new maternal risk loci

GEITP is aware that this project has been a focus of Ge Zhang [Division of Genetics, Cincinnati Children’s Hospital] for >6 years; finally, the results are published and can be shared [see attached]. 😊 More than 15 million pregnancies per … Continue reading

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The crusade against carbon dioxide and integrity in climate science

In September 2023, Princeton University’s Cyrus Fogg Brackett Professor Emeritus of Physics, William Happer, spoke at the Institute of Public Affairs (IPA) to an audience in Brisbane, Australia about the crusade against carbon dioxide and integrity in climate science. Will … Continue reading

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Pioneers of mRNA COVID vaccines win the 2023 Medicine Nobel

As I understand it — here is yet another example of a grad student or postdoc (perhaps in particular because she was a female?) being ridiculed, or passed over, while it was her original idea that represented the breakthrough. But … Continue reading

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Tasmanian tiger RNA is first to be recovered from an extinct animal

This technical breakthrough — boggles the mind. 😉 DwN 19 September 2023 Tasmanian tiger RNA is first to be recovered from an extinct animal Genetic sequences from a museum specimen offer fresh clues about the physiology of thylacines, which went … Continue reading

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