Coffee may come with a cancer warning in California; and a sobering reflection on Paracelsus

Here is yet another example in which Irrationality (disguised as ‘scientific studies’) supercedes Rationality –– leading to fear-mongering, anxiety, and inconvenience to the American consumer. As scientific instrumentation continues to become more precise, we can measure amounts of chemical contaminations at increasingly lower levels. Remember (from elementary chemistry class) that 1 mole of any chemical = 6.022 x 1023 molecules of any substance, and a 1 Molar solution = 6.022 x 1023 grams (divided by its molecular weight) in one Litre of water or other liquid.

So, technically, anything below Avogardo’s Number (6.022e–23, also written as 6.022 x 10–23) would mean less than one molecular of a chemical (such as, in the article below, acrylamide) per Litre. “Micromolar” denotes 10–6 moles/L.” “Picomolar” denotes 10–12 moles/L.” “Femtomolar” denotes 10–15 moles/L.” “Attomolar” denotes 10–18 moles/L.” Scientists can now detect attomolar concentrations of recreational drugs in creek or river samples. Given the new methodology of whole-genome analysis of single cells, we are now approaching attomolar concentrations and below. However, as Paracelsius (1493–1541) wrote, and it is never more true than today’s journalism’s hype and hysteria, “Alle Dinge sind Gift, und nichts ist ohne Gift; allein die dosis machts, daß ein Ding kein Gift sei.“ [Everything is poison, there is nothing that is not poison; the dose alone is what is important as to whether or not a substance is poison.]

In fact, the Bruce Ames lab (in the early 1970s) had already determied that the amount oof acrylamide in a piece of bread that had been toasted is able to be detected as mutations in a bacterial assay. So, here we are, 45+ years later, re-confirming in California, what Ames had already demonstrated (in California). What goes around, comes around. Journalists want to sell newspapers, but when this hype results in public regulations and policy that affect consumers and their pocketbooks –– this has gone from the ridiculous to the sublime. Yes, this is another example of the Linear-No-Threshold (LNT) Model that had been pushed through (way back in the 1940s by Mueller) in the absence of sufficient scientific fact to support such policy.

Coffee may come with a cancer warning in California
By Jen Christensen, CNN
Thurs February 1, 2018
· Roasting coffee beans creates acrylamide, a chemical linked to cancer in rodents
· A California judge will decide whether stores that sell coffee need to warn about the chemical

(CNN) California coffee shops may soon be forced to warn customers about a possible cancer risk linked to their morning jolt of java.

The state keeps a list of chemicals it considers possible causes of cancer, and one of them, acrylamide, is created when coffee beans are roasted.

A lawsuit first filed in Los Angeles County Superior Court in 2010 by the nonprofit Council for Education and Research on Toxics targets several companies that make or sell coffee, including Starbucks, 7-Eleven and BP. The suit alleges that the defendants “failed to provide clear and reasonable warning” that drinking coffee could expose people to acrylamide.

The court documents state that, under the California Safe Drinking Water and Toxic Enforcement Act of 1986, also known as Proposition 65, businesses must give customers a “clear and reasonable warning” about the presence of agents that affect health — and that these stores failed to do so.

Is coffee healthy?

In addition to paying fines, the lawsuit wants companies to post warnings about acrylamide with an explanation about the potential risks of drinking coffee. If the suit is successful, the signs would need to be clearly posted at store counters or on walls where someone could easily see them when making a purchase.

“I’m addicted to coffee, I confess, and I would like to be able to have mine without acrylamide,” Metzger said.

At a bench trial last fall, the coffee companies argued that the level of acrylamide in coffee should be considered safe under the law and that the health benefits of coffee essentially outweigh the risk.

At least 13 of the defendants have settled and agreed to give a warning, most recently 7-Eleven, according to Metzger. The convenience store chain did not respond to requests for comment.

The other manufacturers would have to follow suit if they don’t settle the lawsuit and if the judge finds that they violated state laws. Metzger said private mediation with the remaining retailers is set for February 8. It will include nine of the defendants, and the parties will try to come to an agreement about the case. Otherwise, a judge would probably reach a decision this year.

BP did not return requests for comment. Starbucks referred questions to the National Coffee Association, the industry’s trade association, which said it was not in a position to comment on the litigation.

Bill Murray, the association’s president and CEO, said in a statement, “Coffee has been shown, over and over again, to be a healthy beverage. The US Government’s own Dietary Guidelines state that coffee can be part of a healthy lifestyle. This lawsuit simply confuses consumers, and has the potential to make a mockery of Prop 65 cancer warning at a time when the public needs clear and accurate information about health.”
Health effects of coffee: Where do we stand?

Health effects of coffee: Where do we stand?

Coffee has been much studied over the years, and research has shown that it provides several health benefits, including lowering your risk of early death. It may reduce your risk of heart disease, multiple sclerosis, type 2 diabetes, Alzheimer’s and even some cancers like melanoma and prostate cancer. However, a review by the International Agency for Research on Cancer, a branch of the World Health Organization, found that drinking very hot beverages was “probably carcinogenic to humans” due to burns to the esophagus; there was no relation to the chemical acrylamide.

The science on human exposure to acrylamide still needs “future studies,” according to a 2014 review of scientific research on the chemical’s relationship to a wide variety of cancers in the Journal of Nutrition and Cancer.

In addition to coffee, acrylamide can be found in potatoes and baked goods like crackers, bread and cookies, breakfast cereal, canned black olives and prune juice, although its presence is not always labeled. It’s in some food packaging and is a component of tobacco smoke. According to the National Cancer Institute, people are exposed to “substantially more acrylamide from tobacco smoke than from food.”

In 2002, the International Agency for Research on Cancer classified acrylamide as a group 2A carcinogen for humans based on studies done in animals. Studies done on humans have found “no statistically significant association between dietary acrylamide intake and various cancers,” according to the 2014 research review.

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A few additional studies have seen an increased risk for renal, ovarian and endometrial cancers; however, “the exposure assessment has been inadequate leading to potential misclassification or underestimation of exposure,” according to the 2014 research review.

Even the studies showing cancer links between acrylamide in rats and mice used doses “1,000 to 100,000 times higher than the usual amounts, on a weight basis, that humans are exposed to through dietary sources,” the research review said.

Humans are also thought to absorb acrylamide at different rates and to metabolize it differentlythan rodents, earlier research showed.The National Toxicology Program’s Report on Carcinogens considers acrylamide to be “reasonably anticipated to be a human carcinogen.”

The Food and Drug Administration website says it “is still in the information gathering stage” on the chemical, but the FDA gave consumers suggested ways to cut it out of their diet. The FDA also provided guidance to the industry intended to suggest a range of approaches companies could use to reduce acrylamide levels. The recommendations are only a guide and are “not required,” according to the website.

California added acrylamide to its carcinogen list in January 1990, and the state has successfully taken companies to court over it.

In 2008, the California attorney general settled lawsuitsagainst Heinz, Frito-Lay, Kettle Foods and Lance Inc. when the companies agreed to reduce the levels of acrylamide found in potato chips and French fries.

In 2007, fast-food restaurants in California posted acrylamide warnings about fries and paid court penalties and costs for not posting the warnings in prior years. “We have a huge cancer epidemic in this country, and about a third of cancers are linked to diet,” Metzger said. “To the extent that we can get carcinogens out of the food supply, logically, we can reduce the cancer burden in this country. That’s what this is all about.”

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