Category Archives: Center for Environmental Genetics

Global warming is not settled science:

Global warming is not settled science: This appeared in The Oregonian, on July 13, 2014: Guest columnist D.W.Nebert, MD Daniel Nebert, MD, is professor emeritus at the Cincinnati College of Medicine and Cincinnati Children’s Hospital. The 2013 report by the … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Global warming is not settled science:

Three U of O Professors Observing COVID-19 in Italy Offer Advice to Oregonians

Daniel W Nebert Mon 3/16/2020 2:54 PM Here is advice from three professors, currently quarantined in a small town in northern Italy. Three U of O Professors Observing COVID-19 in Italy Offer Advice to Oregonians “Work from home, have phone … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Three U of O Professors Observing COVID-19 in Italy Offer Advice to Oregonians

CRISPR-Cas9-Mutated PXR Retains Pregnenolone-induced Expression of yp3a65 in Zebrafish

Pregnane-X receptor (PXR; encoded by mammalian NR1I2 gene) is a nuclear receptor (NR) that regulates transcriptional responses to certain drugs and environmental toxicants — in part by inducing transcription of one or more cytochrome P450 3A enzymes that are found … Continue reading

Posted in Center for Environmental Genetics | Comments Off on CRISPR-Cas9-Mutated PXR Retains Pregnenolone-induced Expression of yp3a65 in Zebrafish

Europe’s Coronavirus Fate Is Already Sealed

Daniel W Nebert Sat 3/14/2020 7:50 PM WSJ online March 12, out in print morning of March 13. I don’t think this author (or this article) is endorsing government-funded universal healthcare for all. Sorry, Bernie. Sorry, Joe Biden… ☹ Europe’s … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Europe’s Coronavirus Fate Is Already Sealed

A warming light at the end of the COVID-19 tunnel?

A warming light at the end of the COVID-19 tunnel? March 13, 2020 Gregory Wrightstone A study released March 9 provides some comfort to a panicked world over the continued possible spread of the COVID-19 virus and predicts limiting factors … Continue reading

Posted in Center for Environmental Genetics | Comments Off on A warming light at the end of the COVID-19 tunnel?

Environmental signal, “stress”, in mice helps explain why hair can turn prematurely grey

Stress has been associated with a variety of changes in many tissues, including premature hair-greying. However, whether external stressors are the causal factors, and whether stress-related changes occur at the level of somatic stem cells — remain poorly understood. Hair … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Environmental signal, “stress”, in mice helps explain why hair can turn prematurely grey

Evidence that ancient Europeans carried Neanderthal DNA back to Africa

Studies of ancient DNA are transforming our understanding of human evolutionary history and, in particular, how admixture (presence of DNA in an individual from a distantly-related population, as a result of interbreeding between populations who have been reproductively isolated and … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Evidence that ancient Europeans carried Neanderthal DNA back to Africa

Maternal diabetes and obesity influence the fetal epigenome in a largely Hispanic population

Alarming rates of increase in childhood obesity and type-2 diabetes (T2D) are being seen in the U.S. In 2015, an estimated 30.3 million people in the U.S. had T2D. Approximately 12.7 million children and adolescents — ages 2 to 19 … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Maternal diabetes and obesity influence the fetal epigenome in a largely Hispanic population

Information about COVID-19

I am forwarding the following information which I have received from an internet buddy; I’ve not been able to fact-check all the items, but they all seem very reasonable. Stay well The new coronavirus may not show any signs of … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Information about COVID-19

Ancestral receptor plays a key role in host detection by malaria-carrying mosquitoes

Malaria is caused by protozoan Plasmodium spp. parasites — transmitted by blood-feeding anopheline mosquitoes. Host-seeking by mosquitoes (and other pathogen-spreading insects) relies on the detection of host-associated cues [e.g. carbon dioxide (CO2), odors, and body heat; see especially the diagram … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Ancestral receptor plays a key role in host detection by malaria-carrying mosquitoes