Category Archives: Center for Environmental Genetics

Radiographic assessment of the skeletons of Dolly and other clones finds no abnormal age-related osteoarthritis (OA)

Posted in Center for Environmental Genetics | Comments Off on Radiographic assessment of the skeletons of Dolly and other clones finds no abnormal age-related osteoarthritis (OA)

Autoimmune diseases are more likely to appear — years after having received cancer drugs of the class “checkpoint inhibitors”

It has long been known that successful cancer chemotherapy, especially in children, can lead subsequently to secondary tumors occurring later in life –– undoubtedly due to the mutagenic properties of the cancer-treating drug. The attached one-page article tells the story … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Autoimmune diseases are more likely to appear — years after having received cancer drugs of the class “checkpoint inhibitors”

Buying an “inbred mouse” for your experiments — might not be as homogeneous and stable, from year to year, as you think …..

As these GEITP pages have described several times before, “purely inbred mouse lines,” as well as established cell culture lines, are almost always subject to change, and scientific researchers need to be aware of, and on the lookout for, such … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Buying an “inbred mouse” for your experiments — might not be as homogeneous and stable, from year to year, as you think …..

Previous history of biology preprints: A forgotten experiment from the 1960s

This [attached] article is an intriguing bit of history about scientific “preprint” publications. Since 1991, physicists and mathematicians have been using the arXiv preprint repository to circulate articles and ideas, to the envy of many biologists. After a number of … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Previous history of biology preprints: A forgotten experiment from the 1960s

Oral statins appear to help the host in combating antibiotic-resistant bacteria

Cell integrity depends on the precise organization of its limiting cell membranes, whose molecular organization we understand poorly. The established dogma about the fluid mosaic model had suggested that membrane proteins and lipids diffuse freely and therefore are homogenously distributed. … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Oral statins appear to help the host in combating antibiotic-resistant bacteria

MORE: Dilemma: the rise of the predatory journal

Below is another horror story that Professor Eaton wishes to share with everyone. Because I receive 20-30 of these bogus emails each day, I could offer perhaps some insight to one or several “key words” that I see in virtually … Continue reading

Posted in Center for Environmental Genetics | Comments Off on MORE: Dilemma: the rise of the predatory journal

Dilemma: the rise of the predatory journal

These GEITP pages will continue to share horror stories related to these “online open-access predatory journals” that have exploded in number during the past decade. This one today should be especially of interest to dog lovers. Dog of a dilemma: … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Dilemma: the rise of the predatory journal

Sequencing of ancient genomes from southern Africa — helps in estimating modern human divergence between 350K and 260K years ago

As discussed many times on these GEITP pages –– archaeological, fossil, and genetic data have positioned the early traces of anatomically modern humans in sub-Saharan Africa. The earliest (completely) modern human remains, dating to ~190,000 years ago, originate from Ethiopia. … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Sequencing of ancient genomes from southern Africa — helps in estimating modern human divergence between 350K and 260K years ago

Reviewer bias in single- versus double-blind peer review

Peer review (colleagues, peers, reviewing a manuscript submitted for publication in some journal) can be “single-blind” (reviewers are aware of the names and affiliations of paper authors), or “double-blind” (this information is hidden from the Reviewer). Noticing that computer-science research … Continue reading

Posted in Center for Environmental Genetics | Comments Off on Reviewer bias in single- versus double-blind peer review

CRISPR/Cas9 technology is already being superceded by more accurate (fewer downstream non-targets affected) single-DNA or -RNA editing

Ever since the start of the CRISPR craze 5 years ago, scientists have raced to invent ever-more-versatile, or efficient, variations of this powerful tool, which vastly simplifies the editing of DNA (e.g. instead of requiring 4-6 months to create a … Continue reading

Posted in Center for Environmental Genetics | Comments Off on CRISPR/Cas9 technology is already being superceded by more accurate (fewer downstream non-targets affected) single-DNA or -RNA editing