Monthly Archives: July 2019

Excellent summary from several difference scientific sources on global climate change

This is an EXCELLENT summary from several difference scientific sources — appearing in https//finance.townhall.com — that should (or could) clarify the minds of non-scientists who do not understand Climatology, and how complex it is. Anyone with an open mind, or … Continue reading

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Key metabolic gene for recurrent freshwater colonization and radiation in fish

This story is a great example of gene-environment interactions. When organisms evolve — so that they might occupy a new environment — what adaptations in the genome are required for this transition? Authors [see attached article & editorial] have determined … Continue reading

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Vision using multiple distinct rod opsins in deep-sea fishes

Why is this topic chosen for today’s GEITP email? Well, “light” is an environmental signal, and “genes” within the genome that respond to this signal, are responsible for the “vision” phenotype (trait). And, during evolution, “vision” of course was extremely … Continue reading

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Oligogenic inheritance of a human heart disease involving a genetic modifier

Noll, I stand corrected. 😊 Obviously — I am misusing the term “compound heterozygosity” (and I wondered about that, as I wrote it). Perhaps “tri-allelic recessive heterozygosity” is a better term. Or, as the authors have in the title of … Continue reading

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Study of multiethnic genomes identifies 27 genetic variants associated with disease

This article is a semi-lay summary of a publication soon to appear in Nature. As most of us would expect — the genomes of different ethnic groups exhibit ethnicity-specific alleles (mutations in at least one of the two alleles of … Continue reading

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Some thoughts on the utilization of polygenic risk scores (PRSs) for therapeutic targeting

These GEITP pages have often discussed genome-wide association studies (GWAS), in which a phenotype (i.e. trait — such as height or cancer) is selected by a research team, and then the genomes of hundreds or many thousands of subjects are … Continue reading

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