Monthly Archives: September 2017

Prevention of newborn infections and systemic sepsis by using probiotics in an India rural population

“Sepsis” is a clinical syndrome characterized by systemic inflammation and circulatory compromise initiated by an infection. For those of us who have experienced working in newborn and premie nurseries, especially in county hospitals or rural settings, we know well that … Continue reading

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CRISPR/Cas9-edited correction of an autosomal dominant gene mutation responsible for hypertrophic cardiomyopathy (cause of sudden death in otherwise healthy young athletes)

This is a follow-up of the layman’s article that GEITP previously shared on Aug 3 [from The New York Times, see below]. To reiterate, autosomal dominant mutations are inherited (from parent to child) as a single copy of a defective … Continue reading

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NTP News: Peer Review of the Draft NTP Approach to Genomic Dose-Response Modeling and Webinar Series

Some of you will be interested in attending this National Toxicology Program (NTP) meeting on Genomic Dose-Response Modeling. I see that two webinar dates (Aug 31, Sept 1) have already come and gone, but the Sept 13 and 25 webinar … Continue reading

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**HGNC Newsletter** Summer 2017

Some of you will be interested in the summer 2017 issue of the Human Gene Nomenclature Committee (HGNC) NewsLetter [below]. There are currently 41,158 approved human gene symbols In this newsletter: New VGNC gene nomenclature for cow, dog and horse! … Continue reading

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Spontaneous mutation rate is a plastic trait associated with population density across many domains of life

Spontaneous genetic mutations occur during DNA replication and cell division and is a process deeply embedded in evolution. As we at GEITP have previously discussed, mutagenesis is also central in causing bacterial antibiotic resistance to drugs as well as cancer … Continue reading

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Gut microbes can alter tumor sensitivity by re-wiring tumor-cell signaling !!

As these GEITP emails have previously discussed –– whether it’s a bacterial infection being treated with an antibiotic or a malignant tumor being treated with a chemotherapeutic agent –– mutations in the genome (of the bacterium, or the cancer) often … Continue reading

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