Monthly Archives: March 2017

The end of the linear-no-threshold (LNT) model, after trying to keep it going for almost nine decades

This tongue-in-cheek dry humor [attached article] is designed to underscore the concept that “consensus theories” that have been set up and propagated on false or faked data will eventually become exposed for what they are. The linear dose-response relationship for … Continue reading

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Prevalence and architecture of de novo mutations responsible for developmental disorders in children

Genomes of patients having severe, undiagnosed developmental disorders are well known to be enriched in damaging de novo mutations (DNMs) in developmentally important genes. The attached paper describes the whole-exome sequencing (WES) of 4,293 families containing individuals with developmental disorders. … Continue reading

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Evidence for early life (3.8 to 4.3 billion years ago) in Earth’s oldest hydrothermal vent precipatates

Although it is not known for certain when or where life on Earth began, many evolutionary biologists would agree that some of the earliest habitable environments most likely would have included oceanic hydrothermal vents. In the attached report, authors provide … Continue reading

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DNA damage during isolation and preparation can cause problems in the 1000 Genomes Project and other sequencing repositories

This study [attached] is perhaps not too surprising. And it’s something that everyone should be constantly on the lookout for. As in all scientific experiments, technical problems can lead to mistakes, even making it into the final published form/data set. … Continue reading

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Evolving as a holobiont

During this past decade, scientists have come to realize the importance of all the bacteria, fungi, and other single-celled microorganisms living in our gastrointestinal (GI) tract. As mentioned before on these GEITP pages, total DNA content of a human includes … Continue reading

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How human cultures have adapted to environmentally high levels of arsenic in drinking water

Darwin said it all, back in the mid-19th century. “As organisms live for many generations –– in the same environment with its various adversities, –– ‘survival of the fittest’ will occur.”  In other words, DNA sequence mutations or epigenetic effects … Continue reading

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