Monthly Archives: July 2016

Studying concomitantly both gene expression profiling and protein expression profiling

The “genome” comprises all the genes of a species, aligned in linear fashion along the chromosomes. One chromosome contains the “haploid genome” (about 3 x 109 nucleotides) Both chromosomes (all pairs of chromosomes) contain the “diploid genome” (~6 x 109 nucleotides). The … Continue reading

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NAD+ is able to slow, or actually improve, stem cell loss and aging

Humankind has forever searched for the proverbial “Fountain of Youth.” How can “The aging process” be slowed down, or prevented entirely? Interventions that can slow mammalian aging have been rare. The two attached major articles and one editorial highlight nicotinamide … Continue reading

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Low levels of radiation treatment of Alzheimer Disease

This article––even though it is a case report of one patient––is sufficiently intriguing to share, … supporting the “Hysteresis Model” (small doses of toxic agents can be beneficial) rather than the “Linear No-Threshold (LNT) Model“. Alzheimer disease (AD) primarily affects … Continue reading

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Endogenous caspase-11 ligand elicits IL1 release from (living) dendritic cells

Innate immune cells act as a surveillance system, detecting and responding to pathogens and endogenous danger signals. The complex patterns of signals that are received are detected by a variety of pattern recognition receptors (PRRs). In the main article [attached] … Continue reading

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Combining statistical reasoning … with … scientific reasoning

Imagine the American Physical Society (APS) convening a panel of experts to issue a missive to the scientific community on the difference between weight and mass. And imagine that the motivation for such a message was recognizing that engineers and … Continue reading

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Why sequence the Petunia genome? Because it’s a favorite domestic flower, plus it’s related to the tomato and potato !!

Domestication of plants is often thought to apply principally to food crops, but cultivation has also been widely used to enhance the beauty of orna­mental plants. Writing in Nature Plants [attached], authors report the genome sequences of two progenitor species … Continue reading

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